According to the definition set out in the Charter of European Spatial Planning, regional planning expresses geographically the economic, social, cultural, and ecological policies of society. It is a scientific field, an administrative technique and a policy that was developed with the aim of balanced regional development and the physical organization of a territory. The aim of the Course is to introduce the basic principles and tools of regional planning focusing on the EU countries. The course introduces the student to critical knowledge of the characteristics and the complex structure of the territory, compare the different disciplinary approaches, define the structure and settlement patterns results from a combination of economic, social, cultural, and political dynamics. It analyzes the contemporary issues and current debates regarding regional policies, spatial planning system, spatial governance, environmental issues, urban transformation, rural and disadvantaged areas revival, sustainable development, cultural heritage management, disaster mitigation and urban risk management.